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Hypokalemia Caused by Quetiapine and Risperidone Treatment in Schizophrenia: A Case Report
  1. Qiongwei Yang1,2,
  2. Xiaoyun Guo1 and
  3. Dengtang Liu1
  1. 1First-episode Schizophrenia and Early Psychosis Program, Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  2. 2Minkang Hospital of Ningxia Civil Affairs Department, Ningxia, China
  1. correspondence: Dengtang Liu & Xiaoyun Guo. Mailing address: 600 South Wanping RD, Shanghai, China. Postcode: 200030. E-Mail: xiaoyunguo{at} (Xiaoyun Guo); erliu110{at} (Denglang Liu)


Hypokalemia can cause abnormalities in multiple systems. Long term use of antipsychotic medications can lead to electrolyte imbalance, including hypokalemia. We report a 49-year-old female patient with schizophrenia who developed hypokalemia after oral quetiapine and risperidone treatments. Her blood potassium became normal after she switched to another antipsychotic drug (amisulpride). In addition, we discuss the potential mechanism of antipsychotic drugs leading to hypokalemia and clinical cautions.

  • Hypokalemia
  • somatic
  • quetiapine
  • risperidone
  • antipsychotic drugs
  • schizophrenia

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