Real-world effectiveness of antipsychotic treatment in psychosis prevention in a 3-year cohort of 517 individuals at clinical high risk from the SHARP (ShangHai At …
Objective: Antipsychotics are widely used for treating psychosis, but it is unclear whether
they can also prevent psychosis. This study attempted a longitudinal evaluation of …
they can also prevent psychosis. This study attempted a longitudinal evaluation of …
Changes in inflammatory balance correlates with conversion to psychosis among individuals at clinical high-risk: a prospective cohort study
Previous studies have revealed that the imbalance between Th1 cytokines and Th2
cytokines plays a role in disturbance of cellular responses in the brain during psychosis …
cytokines plays a role in disturbance of cellular responses in the brain during psychosis …
Multivariate joint models for the dynamic prediction of psychosis in individuals with clinical high risk
This study attempted to construct and validate dynamic prediction via multivariate joint
models and compare the prognostic performance of these models to both static and …
models and compare the prognostic performance of these models to both static and …
[HTML][HTML] Tumor necrosis factor-α variations in patients with major depressive disorder before and after antidepressant treatment
L Yao, LH Pan, M Qian, W Sun, CH Gu… - Frontiers in …, 2020 - frontiersin.org
Tumor necrosis factor-α (TNF-α) had been identified as a key pro-inflammatory cytokine in
the pathophysiology of major depressive disorder (MDD) and the mechanism of …
the pathophysiology of major depressive disorder (MDD) and the mechanism of …
Conversion to psychosis in adolescents and adults: similar proportions, different predictors
BackgroundAge effects may be important for improving models for the prediction of
conversion to psychosis for individuals in the clinical high risk (CHR) state. This study aimed …
conversion to psychosis for individuals in the clinical high risk (CHR) state. This study aimed …
[HTML][HTML] Serum complement proteins rather than inflammatory factors is effective in predicting psychosis in individuals at clinical high risk
Immunological/inflammatory factors are implicated in the development of psychosis.
Complement is a key driver of inflammation; however, it remains unknown which factor is …
Complement is a key driver of inflammation; however, it remains unknown which factor is …
Neurocognitive assessments are more important among adolescents than adults for predicting psychosis in clinical high risk
Background Few studies have examined the effects of age on neurocognition to predict
conversion to psychosis in individuals at clinical high risk (CHR). This study aimed to …
conversion to psychosis in individuals at clinical high risk (CHR). This study aimed to …
Temporal dynamics in degree centrality of brain functional connectome in first-episode schizophrenia with different short-term treatment responses: a longitudinal …
Purpose This study investigated temporal dynamics in degree centrality (DC) of the brain
functional connectome in first-episode schizophrenia with different short-term treatment …
functional connectome in first-episode schizophrenia with different short-term treatment …
Serum levels of tumor necrosis factor-α and vascular endothelial growth factor in the subtypes of clinical high risk individuals: a prospective cohort study
Introduction Numerous studies have established the roles of inflammation and angioneurins
in the pathogenesis of schizophrenia (SCZ). This study aimed to compare the serum levels …
in the pathogenesis of schizophrenia (SCZ). This study aimed to compare the serum levels …
A potential objective marker in first-episode schizophrenia based on abnormal niacin response
The lack of objective diagnostic markers has long been a challenge in the clinical
management of schizophrenia (SZ). The current bivariate cut-offs method is an objective …
management of schizophrenia (SZ). The current bivariate cut-offs method is an objective …