Variations of human leukocyte antigen (HLA) genes in the major histocompatibility complex
region (MHC) significantly affect the risk of various diseases, especially autoimmune …

Posttraumatic growth (PTG) is a process of personal transformation following a traumatic life
event in domains of life appreciation, interpersonal relationships, recognition of personal …

Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge,,,–
. Here we conducted a genome-wide association study (GWAS) involving 2,393 cases of …

Conventional human leukocyte antigen (HLA) imputation methods drop their performance
for infrequent alleles, which is one of the factors that reduce the reliability of trans-ethnic …

Atopic dermatitis (AD) is a skin disease that is heterogeneous both in terms of clinical
manifestations and molecular profiles. It is increasingly recognized that AD is a systemic …

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in
over 176,000 individuals with Parkinson's disease (PD) and Alzheimer's disease (AD) …

Background Despite evidence for the role of human leukocyte antigen (HLA) in the genetic
predisposition to Parkinson's disease (PD), the complex haplotype structure and highly …

Abstract Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease
that has caused millions of deaths, where comprehensive understanding of disease …

Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host
Genetics Initiative genome-wide association study used common variants to identify multiple …

Hunner-type interstitial cystitis (HIC) is a rare, chronic inflammatory disease of the urinary
bladder with unknown etiology and genetic background. Here, we conduct a genome-wide …