[PDF][PDF] Immunological effects of silica and asbestos

T Otsuki, M Maeda, S Murakami, H Hayashi… - Cell Mol …, 2007 - researchgate.net
Silicosis patients (SILs) develop respiratory fibrosis and impaired their pulmonary function.
In addition, silica is known as one of the strongest environmental substances causing …

[HTML][HTML] Asbestos-induced cellular and molecular alteration of immunocompetent cells and their relationship with chronic inflammation and carcinogenesis

H Matsuzaki, M Maeda, S Lee, Y Nishimura… - BioMed Research …, 2012 - hindawi.com
Asbestos causes lung fibrosis known as asbestosis as well as cancers such as malignant
mesothelioma and lung cancer. Asbestos is a mineral silicate containing iron, magnesium …

Dysregulation of the immune system caused by silica and asbestos

M Maeda, Y Nishimura, N Kumagai… - Journal of …, 2010 - Taylor & Francis
Silica and asbestos cause pneumoconioses known as silicosis and asbestosis, respectively,
that are each characterized by progressive pulmonary fibrosis. While local effects of inhaled …

E prostanoid 2 (EP2)/EP4‐mediated suppression of antigen‐specific human T‐cell responses by prostaglandin E2

M Okano, Y Sugata, T Fujiwara, R Matsumoto… - …, 2006 - Wiley Online Library
Summary Prostaglandin E2 (PGE2) is a lipid mediator that displays important
immunomodulatory properties, such as polarization of cytokine production by T cells. Recent …

[HTML][HTML] Development of a COVID-19 vaccine effectiveness and safety assessment system in Japan: the VENUS study

H Fukuda, M Maeda, F Murata - Vaccine, 2023 - Elsevier
Background There are currently no COVID-19 vaccine assessment systems in Japan that
allow for the active surveillance of both vaccinated and unvaccinated persons. Herein, we …

Environmental factors producing autoimmune dysregulation–chronic activation of T cells caused by silica exposure

S Lee, H Hayashi, M Maeda, Y Chen, H Matsuzaki… - Immunobiology, 2012 - Elsevier
Autoimmune disorders are induced by various environmental and occupational substances.
Among the most typical factors involving these substances, it is well known that silica …

[HTML][HTML] Acute and delayed psychiatric sequelae among patients hospitalised with COVID-19: a cohort study using LIFE study data

F Murata, M Maeda, C Ishiguro, H Fukuda - General psychiatry, 2022 - ncbi.nlm.nih.gov
Background Characterising the psychiatric sequelae of coronavirus disease 2019 (COVID-
19) can inform the development of long-term treatment strategies. However, few studies …

Regional disparity of reperfusion therapy for acute ischemic stroke in japan: a retrospective analysis of nationwide claims data from 2010 to 2015

M Maeda, H Fukuda, R Matsuo, T Ago… - Journal of the …, 2021 - Am Heart Assoc
Background We aimed to determine whether a regional disparity exists in usage of
reperfusion therapy (intravenous recombinant tissue plasminogen activator [IV rt‐PA] and …

[HTML][HTML] Structural features of free N-glycans occurring in plants and functional features of de-N-glycosylation enzymes, ENGase, and PNGase: the presence of …

M Maeda, Y Kimura - Frontiers in plant science, 2014 - frontiersin.org
Free N-glycans (FNGs) are present at micromolar concentrations in plant cells during their
differentiation, growth, and maturation stages. It has been postulated that these FNGs are …

[HTML][HTML] Silica exposure and altered regulation of autoimmunity

S Lee, H Matsuzaki, N Kumagai-Takei… - … health and preventive …, 2014 - Springer
Silica particles and asbestos fibers, which are known as typical causatives of
pneumoconiosis, induce lung fibrosis. Moreover, silicosis patients often complicate with …