User profiles for "author:Manish Kandpal"
 | Manish KandpalUniversity of Massachusetts Medical school Verified email at umassmed.edu Cited by 787 |
The Warburg effect: insights from the past decade
Several decades ago, Otto Warburg discovered that cancer cells produce energy
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …
Molecular mechanisms underlying occult hepatitis B virus infection
J Samal, M Kandpal… - Clinical microbiology …, 2012 - Am Soc Microbiol
Chronic hepatitis B virus (HBV) infection is a complex clinical entity frequently associated
with cirrhosis and hepatocellular carcinoma (HCC). The persistence of HBV genomes in the …
with cirrhosis and hepatocellular carcinoma (HCC). The persistence of HBV genomes in the …
A G-quadruplex motif in an envelope gene promoter regulates transcription and virion secretion in HBV genotype B
HBV genotypes differ in pathogenicity. In addition, genotype-specific differences in the
regulation of transcription and virus replication exist in HBV, but the underlying mechanisms …
regulation of transcription and virus replication exist in HBV, but the underlying mechanisms …
[HTML][HTML] Genome-wide analysis of G-quadruplexes in herpesvirus genomes
Background G-quadruplexes are increasingly recognized as regulatory elements in human,
animal, bacterial and plant genomes. The presence and function of G-quadruplexes are not …
animal, bacterial and plant genomes. The presence and function of G-quadruplexes are not …
[HTML][HTML] Prevalence of excessive internet use and its correlation with associated psychopathology in 11th and 12th grade students
Background Globally, the number of internet users has crossed the three-billion mark, while
in India users grew over 17% in the first 6 months of 2015 to 354 million. This study …
in India users grew over 17% in the first 6 months of 2015 to 354 million. This study …
CpG dinucleotide frequencies reveal the role of host methylation capabilities in parvovirus evolution
Parvoviruses are rapidly evolving viruses that infect a wide range of hosts, including
vertebrates and invertebrates. Extensive methylation of the parvovirus genome has been …
vertebrates and invertebrates. Extensive methylation of the parvovirus genome has been …
[HTML][HTML] HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene
J Samal, M Kandpal, P Vivekanandan - Scientific reports, 2017 - nature.com
Chronic HBV infection is a major cause of hepatocellular carcinoma (HCC). The association
between hepatitis B “e” antigen (HBeAg) and HCC is well-established by epidemiological …
between hepatitis B “e” antigen (HBeAg) and HCC is well-established by epidemiological …
[HTML][HTML] Hepatitis B “e” antigen-mediated inhibition of HBV replication fitness and transcription efficiency in vitro
J Samal, M Kandpal, P Vivekanandan - Virology, 2015 - Elsevier
A mutation at nucleotide 1896 (G1896A) is the most common cause for the loss of HBeAg. In
contrast to clinical data, cell culture studies report a high-replicating phenotype for the …
contrast to clinical data, cell culture studies report a high-replicating phenotype for the …
Enhanced hepatitis B virus (HBV) pre-genomic RNA levels and higher transcription efficiency of defective HBV genomes
Defective hepatitis B virus (dHBV) particles contain genomes corresponding to singly
spliced HBV RNA. A limited number of studies show that dHBV is present in all chronically …
spliced HBV RNA. A limited number of studies show that dHBV is present in all chronically …
[HTML][HTML] Sleeping beauty: Kleine–Levin syndrome
S Mudgal, RC Jiloha, M Kandpal… - Indian journal of …, 2014 - journals.lww.com
Kleine–Levin syndrome (KLS) alias sleeping beauty syndrome, is a rare sleep disorder.
Clinically presenting as episodes of hypersomnolence, behavioral and cognitive …
Clinically presenting as episodes of hypersomnolence, behavioral and cognitive …