User profiles for "author:Lijuan Pang"

Lijuan Pang

Polyneuron Pharmaceuticals AG
Verified email at polyneuron.com
Cited by 692

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

Y Tang, X Wu, W Lei, L Pang, C Wan, Z Shi, L Zhao… - Nature medicine, 2009 - nature.com
Bone remodeling depends on the precise coordination of bone resorption and subsequent
bone formation. Disturbances of this process are associated with skeletal diseases, such as …

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

L Xian, X Wu, L Pang, M Lou, CJ Rosen, T Qiu… - Nature medicine, 2012 - nature.com
Insulin-like growth factor 1 (IGF-1), the most abundant growth factor in the bone matrix,
maintains bone mass in adulthood. We now report that IGF-1 released from the bone matrix …

[HTML][HTML] Combined transplantation of mesenchymal stem cells and endothelial progenitor cells for tissue engineering: a systematic review and meta-analysis

K Sun, Z Zhou, X Ju, Y Zhou, J Lan, D Chen… - Stem cell research & …, 2016 - Springer
Background Combined cell implantation has been widely applied in tissue engineering in
recent years. In this meta-analysis, we aimed to establish whether the combined …

Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells

X Cao, X Wu, D Frassica, B Yu… - Proceedings of the …, 2011 - National Acad Sciences
Radiation therapy can result in bone injury with the development of fractures and often can
lead to delayed and nonunion of bone. There is no prevention or treatment for irradiation …

Prognostic impact of tumor-associated macrophage infiltration in esophageal cancer: a meta-analysis

J Li, Y Xie, X Wang, F Li, S Li, M Li, H Peng… - Future …, 2019 - Future Medicine
Aim: To provide clarity surrounding the association between tumor-associated macrophages
(TAMs) and esophageal cancer prognosis. Materials & methods: Several databases were …

Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression

Z Li, J Lai, P Zhang, J Ding, J Jiang, C Liu… - Molecular …, 2022 - nature.com
The intricate processes of microbiota-gut-brain communication in modulating human
cognition and emotion, especially in the context of mood disorders, have remained elusive …

FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation

T Klein, D Abgottspon, M Wittwer… - Journal of medicinal …, 2010 - ACS Publications
Urinary tract infection (UTI) by uropathogenic Escherichia coli (UPEC) is one of the most
common infections, particularly affecting women. The interaction of FimH, a lectin located at …

Prognostic value of the Micro RNA‐29 family in multiple human cancers: A meta‐analysis and systematic review

Y Qi, Y Huang, L Pang, W Gu, N Wang… - Clinical and …, 2017 - Wiley Online Library
Micro RNA s (mi RNA s) in cancer development have attracted much attention in recent
years. miR‐29 is known to critically affect cancer progression by functioning as a tumor …

[PDF][PDF] Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling

X Wu, L Pang, W Lei, W Lu, J Li, Z Li, FJ Frassica… - Cell stem cell, 2010 - cell.com
The anabolic effects of parathyroid hormone (PTH) on bone formation are impaired by
concurrent use of antiresorptive drugs. We found that the release of active transforming …

FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile

S Kleeb, L Pang, K Mayer, D Eris, A Sigl, RC Preston… - 2015 - ACS Publications
Urinary tract infections (UTIs), predominantly caused by uropathogenic Escherichia coli
(UPEC), belong to the most prevalent infectious diseases worldwide. The attachment of …