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Systolic vs diastolic blood pressure and the burden of hypertension

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References

  1. The Sixth Report of the Joint National Committee on Prevention, Evaluation, and Treatment of High Blood Pressure Arch Int Med 1997 157: 2413–2446

  2. Chalmers J et al. 1999 World Health Organization-International Society of Hypertension Guidelines for the management of hypertension. Guidelines sub-committee of the World Health Organization Clin Exp Hypertens 1999 21: 1009–1060

    Article  CAS  PubMed  Google Scholar 

  3. Lloyd-Jones DM et al. Differential impact of systolic and diastolic blood pressure level on JNC-VI staging. Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Hypertension 1999 34: 381–385

    Article  CAS  PubMed  Google Scholar 

  4. Franklin SS et al. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives Hypertension 2001 37: 869–873

    Article  CAS  PubMed  Google Scholar 

  5. Pogue VA, Ellis C, Michel J, Francis CK . New staging system of the fifth Joint National Committee Report on the Detection, Evaluation, and Treatment of High Blood Pressure alters assessment of the severity and treatment of hypertension Hypertension 1996 28: 713–718

    Article  CAS  PubMed  Google Scholar 

  6. Banegas JR et al. Systolic versus diastolic blood pressure: community burden and impact on blood pressure staging J Hum Hypertens 2002 16: 163–167

    Article  CAS  PubMed  Google Scholar 

  7. Report of the Joint National Committee on detection, Evaluation, and Treatment of High Blood Pressure: a cooperative study JAMA 1977 237: 255–261

  8. Kannel WB . Elevated systolic blood pressure as a cardiovascular risk factor Am J Cardiol 2000 85: 251–255

    Article  CAS  PubMed  Google Scholar 

  9. Silagy CA, Mcneil JJ . Epidemiologic aspects of isolated systolic hypertension and implications for future research Am J Cardiol 1992 69: 213–218

    Article  CAS  PubMed  Google Scholar 

  10. The Fifth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure Arch Intern Med 1993 153: 154–183

  11. Perry MP et al. Pretreatment blood pressure as a predictor of 21 year mortality Am J Hypertens 2000 13: 724–733

    Article  PubMed  Google Scholar 

  12. Staessen JA et al. Risks of untreated and treated isolated systolic hypertension in the elderly: metaanalysis of outcome trials The Lancet 2000 355: 865–872

    Article  CAS  Google Scholar 

  13. He J, Whelton PK . Elevated systolic blood pressure as a risk factor for cardiovascular and renal disease J Hypertens Suppl 1999 17: S7–S13

    CAS  PubMed  Google Scholar 

  14. Sever P . Abandoning Diastole BMJ 1999 318: 1773–1776

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Swales JD . Systolic versus diastolic pressure: paradigm shift or cycle? J Hum Hypertens 2000 14: 477–479

    Article  CAS  PubMed  Google Scholar 

  16. Nielsen WB, Lindenstrom E, Vestbo J, Jensen GB . Is diastolic hypertension an independent risk factor for stroke in the presence of normal blood pressure in the middle-aged and elderly? Am J Hypertens 1997 10: 634–639

    Article  CAS  PubMed  Google Scholar 

  17. Leonetti G, Cuspidi C, Facchini M, Stramba-Badiale M . Is systolic pressure a better target for antihypertensive treatment than diastolic pressure? J Hypertens Suppl 2000 18: S13–S20

    CAS  PubMed  Google Scholar 

  18. Veterans Administration Cooperative Study on Antihypertensive Agents: Effects of treatment on morbidity in hypertension. 1. Results inpatients with diastolic blood pressures averaging 115 through 129 mm Hg JAMA 1967 202: 1028

  19. Domanski M et al. Cardiovascular risk assessment using pulse pressure in the First National Health and Nutrition Examination Survey (NHANES 1) Hypertension 2000 38: 793

    Article  Google Scholar 

  20. Vaccarino V et al. Pulse pressure and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program Am J Cardiol 2001 88: 980–986

    Article  CAS  PubMed  Google Scholar 

  21. Vaccarino V, Holford T, Krumholtz HM . Pulse pressure and risk for myocardial infarction and heart failure in the elderly J Am Coll Cardiol 2000 36: 130–137

    Article  CAS  PubMed  Google Scholar 

  22. White WB . The systolic blood pressure versus pulse pressure controversy Am J Cardiol 2001 87: 1278–1281

    Article  CAS  PubMed  Google Scholar 

  23. Miura K et al. Pulse pressure compared with other blood pressure indexes in the prediction of 25-year cardiovascular and all-cause mortality rates: The Chicago Heart Association Detection Project in Industry Study Hypertension 2001 38: 232–237

    Article  CAS  PubMed  Google Scholar 

  24. Antikainen RL, Jousilahti P, Vanhanen H, Ruomilehto J . Excess mortality associated with increased pulse pressure among middle-aged men and women is explained by high systolic blood pressure J Hypertens 2000 18: 417–423

    Article  CAS  PubMed  Google Scholar 

  25. O'Brien E, Staessen J . What is hypertension? Lancet 1999 353: 1541–1542

    Article  CAS  PubMed  Google Scholar 

  26. Port S et al. Systolic blood pressure and mortality The Lancet 2000 355: 175–179

    Article  CAS  Google Scholar 

  27. Benetos A et al. Should diastolic and systolic blood pressure be considered for cardiovascular risk evaluation: A study in middle-aged men and women J Am Coll Cardiol 2001 37: 163–168

    Article  CAS  PubMed  Google Scholar 

  28. Franklin SS et al. Is pulse pressure useful in predicting risk for heart disease? Circulation 1999 100: 354–360

    Article  CAS  PubMed  Google Scholar 

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Tin, L., Beevers, D. & Lip, G. Systolic vs diastolic blood pressure and the burden of hypertension. J Hum Hypertens 16, 147–150 (2002). https://doi.org/10.1038/sj.jhh.1001373

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