Secondary outcomes | Subjects | SMDs/RRs (95% CI) | I2 (%) | p-value |
PANSS total scores | 403 | −0.62 (−2.38 to 1.15) | 0 | 0.49 |
Discontinuation due to any reason | 330 | 0.93 (0.63 to 1.37) | 0 | 0.71 |
TESS total scores | 187 | 6.95 (−1.23 to 15.14) | 99 | 0.10 |
Akathisia | 190 | 1.40 (0.46 to 4.22) | 0 | 0.55 |
Constipation | 190 | 1.48 (0.44 to 5.02) | 0 | 0.53 |
Headache | 190 | 0.85 (0.27 to 2.67) | 0 | 0.78 |
PANSS, Positive and Negative Syndrome Scale;
RRs, risk ratios; SMDs, standard mean differences; TESS, Treatment Emergent Symptom Scale.