Table 3

Power estimates from testing the null of no difference between paired outcomes by different methods over M=2000 MC replicates

Sample size	Paired t-test	Signed-rank test	GLMM (Poisson)	GLMM (NB)	GEE	GEE (log-link)
Dispersion parameter
n=10	0.057	0.060	0.406	0.194	0.120	0.178
n=25	0.102	0.100	0.495	0.151	0.132	0.159
n=50	0.190	0.188	0.555	0.214	0.209	0.227
n=100	0.344	0.310	0.718	0.344	0.360	0.373
n=200	0.599	0.555	0.897	0.583	0.607	0.611
Dispersion parameter
n=10	0.119	0.104	0.172	0.161	0.205	0.222
n=25	0.266	0.260	0.333	0.320	0.321	0.331
n=50	0.506	0.490	0.559	0.546	0.535	0.539
n=100	0.834	0.818	0.861	0.858	0.842	0.842
n=200	0.981	0.980	0.988	0.987	0.983	0.983

GEE, generalised estimating equation; GLMM, generalised linear mixed-effects model; MC, Monte Carlo; NB, negative binomial.