Assessments | MDD with suicide risk | MDD without suicide risk | Normal participants | χ2/Z | P value |
(n=22) | (n=19) | (n=21) | |||
Demographic characteristics, (mean (SD)) | |||||
Age (years) | 28.7 (4.2) | 34.3 (7.2) | 28.8 (3.6) | 9.05 | 0.011 |
Height (cm) | 163.4 (5.6) | 165.3 (5.8) | 165.1 (7.2) | 0.96 | 0.619 |
Weight (kg) | 58.0 (10.4) | 59.5 (12.1) | 58.4 (8.7) | 0.32 | 0.854 |
BMI (kg/m²) | 21.8 (3.5) | 21.6 (3.1) | 21.3 (2.6) | 0.03 | 0.987 |
Education (years), median (IQR) | 16 (15–16) | 16 (13–16) | 17 (16–19) | 7.47 | 0.024 |
Sex, male, n (%) | 3 (13.6) | 6 (31.6) | 9 (42.9%) | 4.54 | 0.103 |
Clinical characteristics, (median (IQR)) | |||||
HAMA | 14.5 (12.8–18.0) | 13.0 (12.0–15.0) | 2.0 (0.5–2.5) | 45.03 | <0.001 |
HAMD-17 | 25.5 (22.0–29.0) | 21.0 (18.0–24.0) | 2.0 (1.0–3.0) | 41.67 | <0.001 |
PHQ-9 | 21.0 (17.8–23.3) | 13.0 (12.0–15.0) | 2.0 (1.0–3.0) | 46.28 | <0.001 |
MDQ | 3.0 (2.0–4.0) | 2.0 (1.0–3.0) | 1.0 (0.0–2.0) | 13.93 | 0.001 |
PSQI | 13.5 (11.0–17.0) | 13.0 (10.0–15.0) | 3.0 (2.0–5.0) | 39.63 | <0.001 |
Features of peripheral body temperature, (mean (SD)) | |||||
Mesor | 36.17 (0.30)* | 36.22 (0.27)† | 35.84 (0.38) | 11.82 | 0.003 |
Amplitude | 0.38 (0.29) | 0.38 (0.20) | 0.31 (0.14) | 4.09 | 0.130 |
Phase-delay | 4.72 (1.68) ‡ | 3.05 (2.19) | 3.19 (1.82) | 9.68 | 0.008 |
Nadir | 5:00 (2:53) | 5:12 (4:41) | 7:27 (5:33) | 2.88 | 0.237 |
Sex was calculated by χ2 test, statistic value: χ2. Others were calculated by Kruskal-Wallis test, statistic value: Z; p: MDD versus NC at baseline. The differences were determined with significance level of 0.05 and statistically significant results in the table are in boldface.
*Patients with MDD with suicide risk versus NC participants: Z=2.81, p=0.015; patients with MDD with suicide risk versus patients with MDD without suicide risk: Z=0.41, p=0.681.
†Patients with MDD without suicide risk versus NC participants: Z=3.11, p=0.006.
‡Patients with MDD with suicide risk versus MDD without suicide risk: Z=2.52, p=0.035; patients with MDD with suicide risk versus NC participants: Z=−2.81, p=0.015.
BMI, body mass index; HAMA, Hamilton Anxiety Scale; HAMD-17, Hamilton Depression Scale 17 items; MDD, major depressive disorder; MDQ, Mood Disorder Questionnaire; NC, normal control; PHQ-9, Patient Health Questionnaire; PSQI, Pittsburgh Sleep Quality Index.