Table 4

Areas of cortical thickness significantly reduced in patients with Alzheimer’s disease compared with normal controls

Left hemisphereRight hemisphere
Brain regionPeak vertex talairach t P valuesBrain regionPeak vertex talairach t P values
x y zx y z
Precentral gyrus−21.9 −24.9 55.43.2480.002Inferior parietal cortex40.5 −50.5 39.33.0640.003
Pars triangularis−29.8 28.2 7.42.9040.005Precuneus cortex19.8 −56.0 17.42.5240.014
Lateral orbitofrontal cortex−27.0 27.5 −1.22.6650.01Supramarginal gyrus38.4 −42.2 34.82.4910.016
Insula cortex−38.0 1.1 33.52.090.041Superior parietal cortex32.2 −45.5 42.62.3260.024
Superior parietal cortex−17.3 −88.8 19.02.0080.049Postcentral gyrus15.9 −33.1 61.42.3140.024
Precentral gyrus13.8−29.4 58.52.2560.028
Cuneus cortex16.0 −67.1 15.92.1540.035