Table 2

Results of linear regression with self-reported eating disorder symptoms or treatment response as the dependent variables and PPC–IFG connectivity strength as the independent variable

Unstandardised coefficientsStandardised coefficientstP value95% CI (lower to upper)
BSE
Dependent variable: EDE-Q 6.0 total score at baseline
 Constant2.9520.7563.90<0.001(1.445 to 4.459)
 PPC-IFG−4.6501.447−0.356−3.21 0.002 (−7.534 to −1.766)
 Age−0.0240.039−0.066−0.600.551(−0.102 to 0.055)
Dependent variable: overeating at baseline
 Constant−22.62117.081−1.320.190(−56.663 to 11.421)
 PPC-IFG−29.68214.822−0.232−2.00 0.049 (−59.223 to −0.142)
 Age−0.2990.788−0.074−0.380.706(−1.870 to 1.272)
 Age of onset0.5720.9580.1160.600.552(−1.337 to 2.481)
 BMI1.7990.8820.2372.04 0.045 (0.041 to 3.558)
Dependent variable: loss of control at baseline
 Constant−23.02815.309−1.500.137(−53.539 to 7.484)
 PPC-IFG−31.71413.285−0.272−2.39 0.020 (−58.191 to −5.237)
 Age−0.4840.706−0.132−0.690.496(−1.892 to 0.924)
 Age of onset0.8080.8590.1790.940.350(−0.903 to 2.519)
 BMI1.8260.7910.2642.31 0.024 (0.250 to 3.403)
Dependent variable: decrease in EDE-Q 6.0 total score at 4-week follow-up
 Constant5.0473.1401.610.125(−1.551 to 11.644)
 PPC-IFG−4.4351.970−0.472−2.25 0.037 (−8.574 to −0.297)
 Age0.2140.1760.6171.220.240(−0.156 to 0.585)
 Age of onset−0.4900.245−1.042−2.010.060(−1.004 to 0.023)
 BMI0.0080.1410.0110.060.957(−0.288 to 0.304)
Dependent variable: decrease in EDE-Q 6.0 total score at 12-week follow-up
 Constant6.2412.8102.220.038(0.381 to 12.102)
 PPC-IFG−6.8352.782−0.467−2.46 0.023 (−12.639 to −1.032)
 Age0.0070.0790.0240.090.928(−0.158 to 0.172)
 Age of onset−0.2850.147−0.497−1.950.066(−0.591 to 0.021)
 BMI−0.0400.135−0.058−0.300.770(−0.323 to 0.243)
Dependent variable: improvement of loss of control
 Constant1.3840.7711.800.088(−0.224 to 2.993)
 dlPFC-MTG5.0281.8990.5082.65 0.015 (1.067 to 8.989)
 Age−0.0660.042−0.300−1.570.133(−0.154 to 0.022)
Dependent variable: improvement of binge eating
 Constant3.0121.2780.6152.360.046(0.064 to 5.959)
 dlPFC-MTG−0.0630.032−0.859−1.960.086(−0.137 to 0.011)
 Age0.0690.0790.4270.880.405(−0.113 to 0.251)
 Age of onset−0.1020.084−0.400−1.210.262(−0.296 to 0.093)
 BMI3.0121.2780.6152.36 0.046 (0.064 to 5.959)
Dependent variable: improvement of overeating
 Constant−0.0821.045−0.080.938(−2.297 to 2.132)
 dlPFC-SFG4.2741.8120.4902.36 0.031 (0.432 to 8.115)
 Age−0.0590.051−0.241−1.160.264(−0.167 to 0.049)
  • Note: P values in bold indicate P<0.05

  • B, beta; BMI, body mass index; dlPFC, dorsolateral prefrontal cortex; EDE-Q 6.0, Questionnaire Version of the Eating Disorder Examination (version 6.0); IFG, inferior frontal gyrus; MTG, middle temporal gyrus; PPC, posterior parietal cortex; SFG, superior frontal gyrus.