Clinical characteristics and outcomes of study participants
| Patient | Group | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | ||
| Sex | F | F | F | F | F | F | F | 7 F |
| Age (years) | 57 | 60 | 50 | 65 | 61 | 69 | 62 | 60.6 (5.6) |
| Duration of depressive illness since onset (years) | 9 | 8 | 7 | 5 | 4 | 5 | 4 | 6.0 (1.9) |
| Depressive episodes | 6 | 5 | 5 | 4 | 4 | 5 | 4 | 4.7 (0.7) |
| Current depressive episode duration (months) | 5 | 4 | 6 | 4 | 3 | 4 | 5 | 4.4 (0.9) |
| HAMD-17 (total scores) | ||||||||
| Baseline | 29 | 28 | 27 | 26 | 26 | 25 | 24 | |
| Week 4 | 14* | 13* | 12* | 13* | 12* | 10* | 12* | |
| MADRS (total scores) | ||||||||
| Baseline | 33 | 31 | 28 | 29 | 30 | 29 | 28 | |
| Week 4 | 16† | 14† | 13† | 14† | 15† | 13† | 13† | |
*Response defined as HAMD-17 score ≥50% decrease from the baseline.
†Response defined as MADRS score ≥50% decrease from the baseline.
F, female; HAMD-17, 17-item Hamilton Rating Scale for Depression; MADRS, Montgomery-Åsberg Depression Rating Scale.