Baseline characteristics: demographic data of patients with gender dysphoria and study population.
| Patients with gender dysphoria | Study population | P value | |
| Number (%) | Number (%) | ||
| Total | 66 078 | 42 720 215 | |
| Age, mean (SD) | 26 (12) | 34 (17) | <0.001 |
| Sex assigned at birth | |||
| Male | 27 304 (41.3) | 19 190 043 (44.9) | <0.001 |
| Female | 38 093 (57.6) | 23 345 560 (54.6) | <0.001 |
| Unknown | 681 (1.0) | 184 612 (0.4) | <0.001 |
| Ethnicity | |||
| Hispanic/Latino | 5 589 (8.5) | 4 593 152 (10.8) | <0.001 |
| Not Hispanic/Latino | 47 033 (71.2) | 23 140 641 (54.2) | <0.001 |
| Unknown ethnicity | 13 456 (20.4) | 14 986 422 (35.1) | <0.001 |
| Race | |||
| White | 48 137 (72.8) | 24 607 814 (57.6) | <0.001 |
| Unknown | 10 078 (15.3) | 9 907 100 (23.2) | <0.001 |
| Black or African American | 5 869 (8.9) | 6 511 445 (15.2) | <0.001 |
| Asian | 1 326 (2.0) | 1 412 057 (3.3) | <0.001 |
| American Indian or Alaska Native | 592 (0.9) | 213 571 (0.5) | <0.001 |
| Native Hawaiian or Other Pacific Islander | 76 (0.1) | 68 228 (0.2) | 0.004 |
For categorical variables, a Fisher’s exact test was conducted; for continuous variables, a t-test was conducted.
SD, standard deviation.