Table 1

Interaction between antipsychotics and nicotine

Possible effect of nicotine on antipsychotic drug levels (P450)
Antipsychotic medicationNicotine
ClozapineDecreases drug levels
OlanzapineDecreases drug levels
HaloperidolPossibly decreases drug levels
PhenothiazinesDecreases drug levels
RisperidoneNone reported
ZiprasidoneNone reported
QuetiapineNone reported
AripiprazoleNone reported

  • Data adapted from Mago et al.46