Association results of VEGF family genes through logistic regression
Gene | Variants ID | Chr | BP | Function | Allele | Model | Corrected P value | OR (95% CI) |
KDR | rs7692791 | 4 | 55980239 | Intronic | C/T | Additive | 0.015 | 9.584 (1.549 to 59.31) |
Dominant | 0.008 | 30.85 (2.404 to 396.0) | ||||||
rs7667298 | 4 | 55991731 | UTR5 | T/C | Dominant | 0.040 | 0.1258 (0.0173 to 0.9138) | |
IGF-1R | rs1815009 | 15 | 99504671 | UTR3 | C/T | Dominant | 0.026 | 15.75 (1.400 to 177.3) |
rs3743249 | 15 | 99505423 | UTR3 | G/T | Dominant | 0.026 | 15.70 (1.393 to 176.8) | |
rs3743250 | 15 | 99505316 | UTR3 | C/T | Dominant | 0.026 | 15.49 (1.398 to 171.7) | |
rs3743251 | 15 | 99504129 | UTR3 | G/A | Dominant | 0.034 | 14.86 (1.219 to 181.2) |
BP, base-pair position; Chr, chromosome; CI, confidence interval; IGF-1R, insulin-like growth factor receptor 1; KDR, kinase insert domain-containing receptor; OR, odds ratio; VEGF, vascular endothelial growth factor.