Table 2

Quality control process of the genes

GeneSNPDetection rate <90%MAF <0.05HWE <0.05Valid SNP
VEGFA 2850023
VEGFB 7011 (repeat with detection rate <90%, rs199850719)6
KDR 2042 (1 repeat with detection rate <90%, rs199850719)213
FLT-1 2003017
IGF-1 1310012
IGF-1R 32284 (1 repeat with detection rate <90%, rs2715415)19
PlGF 4111 (repeat with detection rate <90%, rs4953402)2
  • FLT-1, Fms-like-tyrosine kinase; HWE, Hardy-Weinberg equilibrium; IGF-1, insulin-like growth factor 1; IGF-1R, insulin-like growth factor receptor 1; KDR, kinase insert domain-containing receptor; MAF, minor allele frequency; PlGF, placental growth factor; SNP, single nucleotide polymorphism; VEGFA, vascular endothelial growth factor A; VEGFB, vascular endothelial growth factor B.