Results of Generalised Summary-data-based Mendelian Randomisation analysis
Exposure trait | Outcome trait | bxy | SE | P value | SNPs |
DBP | Anxiety | 0.012 6 | 0.006 7 | 0.061 | 1087 |
DBP | Depressive symptoms | 0.000 2 | 0.000 9 | 0.828 | 1091 |
DBP | Neuroticism | 0.003 6 | 0.000 8 | <0.001 | 1074 |
DBP | SWB | −0.001 2 | 0.000 8 | 0.111 | 941 |
Hypertension | Anxiety | 0.620 9 | 0.697 7 | 0.374 | 84 |
Hypertension | Depressive symptoms | 0.057 1 | 0.093 0 | 0.540 | 84 |
Hypertension | Neuroticism | 0.188 3 | 0.084 6 | 0.026 | 84 |
Hypertension | SWB | −0.038 8 | 0.080 1 | 0.628 | 68 |
PP | Anxiety | 0.012 7 | 0.006 4 | 0.049 | 842 |
PP | Depressive symptoms | −0.000 5 | 0.000 8 | 0.588 | 836 |
PP | Neuroticism | −0.001 2 | 0.000 8 | 0.119 | 822 |
PP | SWB | 0.001 2 | 0.000 7 | 0.092 | 727 |
SBP | Anxiety | 0.004 2 | 0.004 0 | 0.287 | 1024 |
SBP | Depressive symptoms | −0.000 5 | 0.000 5 | 0.302 | 1024 |
SBP | Neuroticism | 0.000 3 | 0.000 5 | 0.585 | 1006 |
SBP | SWB | 0.000 4 | 0.000 5 | 0.355 | 881 |
DBP, diastolic blood pressure; PP, pulse pressure; SBP, systolic blood pressure; SNPs, single nucleotide polymorphisms; SWB, subjective well-being.