Intraday and interday precision of venlafaxine (VEN) and O-desmethylvenlafaxine (ODV) in plasma
| Samples | Spiked concentration (ng/mL) | Detected concentration (ng/mL) | RSD (intraday n=5) (%) | RSD (interday n=15) (%) |
| ODV | 20 | 20.20 (1.51) | 7.49 | 6.49 |
| 19.98 (1.20) | 6.01 | |||
| 19.92 (1.23) | 6.41 | |||
| 200 | 198.79 (5.41) | 2.72 | 4.21 | |
| 196.36 (9.63) | 4.91 | |||
| 198.75 (10.76) | 5.42 | |||
| 750 | 752.36 (18.30) | 2.43 | 4.57 | |
| 747.74 (20.84) | 2.79 | |||
| 761.05 (55.84) | 7.34 | |||
| VEN | 20 | 20.74 (1.51) | 7.29 | 5.48 |
| 20.89 (1.01) | 6.01 | |||
| 19.92 (0.68) | 3.41 | |||
| 200 | 208.09 (5.32) | 2.56 | 4.06 | |
| 206.75 (6.20) | 4.91 | |||
| 207.41 (13.41) | 6.46 | |||
| 750 | 762.12 (19.02) | 2.50 | 4.86 | |
| 754.54 (17.35) | 2.79 | |||
| 790.78 (56.22) | 7.11 |
RSD, relative SD.