Table 1

Extraction recovery and method recovery of venlafaxine (VEN) and O-desmethylvenlafaxine (ODV) in plasma

SamplesConcentration (ng/mL)Extraction recovery (n=5)Method recovery (n=5)
Mean (%)RSD (%)Mean (%)RSD (%)
ODV2078.53 (1.26)1.60101.78 (6.43)6.31
20070.70 (5.14)7.2799.38 (5.38)5.42
75071.30 (4.08)5.7399.15 (4.86)4.90
VEN2089.36 (4.84)5.42101.78 (5.67)5.57
20083.83 (6.86)8.18103.70 (6.70)6.46
75084.21 (4.08)6.65102.78 (5.73)5.58
  • RSD, relative SD.