RT Journal Article
SR Electronic
T1 Decoding psychosis: from national genome project to national brain project
JF General Psychiatry
JO Gen Psych
FD BMJ Publishing Group Ltd
SP e100889
DO 10.1136/gpsych-2022-100889
VO 35
IS 4
A1 Liya Sun
A1 Manfei Xu
A1 Yongyong Shi
A1 Yifeng Xu
A1 Jinghong Chen
A1 Lin He
YR 2022
UL http://gpsych.bmj.com/content/35/4/e100889.abstract
AB The mind has puzzled humans for centuries, and its disorders, such as psychoses, have caused tremendous difficulties. However, relatively recent biotechnological breakthroughs, such as DNA technology and neuroimaging, have empowered scientists to explore the more fundamental aspects of psychosis. From searching for psychosis-causing genes to imaging the depths of the brain, scientists worldwide seek novel methods to understand the mind and the causes of its disorders. This article will briefly review the history of understanding and managing psychosis and the main findings of modern genetic research and then attempt to stimulate thought for decoding the biological mechanisms of psychosis in the present era of brain science.