PT  - JOURNAL ARTICLE
AU  - Jiayuan Qiu
AU  - Lu Zhao
AU  - Shifu Xiao
AU  - Shaowei Zhang
AU  - Ling Li
AU  - Jing Nie
AU  - Li Bai
AU  - Shixing Qian
AU  - Yang Yang
AU  - Michael Phillips
AU  - Meiqing Sheng
AU  - Yuan Fang
AU  - Xia Li
TI  - Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment
AID  - 10.1136/gpsych-2021-100532
DP  - 2022 Aug 01
TA  - General Psychiatry
PG  - e100532
VI  - 35
IP  - 4
4099  - http://gpsych.bmj.com/content/35/4/e100532.short
4100  - http://gpsych.bmj.com/content/35/4/e100532.full
SO  - Gen Psych2022 Aug 01; 35
AB  - Background The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment, but easy-to-implement management methods are lacking.Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cognitive function of older adults in the community with normal cognition (NC) and mild cognitive impairment (MCI).Methods The comprehensive cognitive health management programme included a psychiatric assessment of the cognitive risk factors for those in the intervention groups and individualised recommendations for reducing the risks through self-management supported by regular medical professional follow-up. The intervention groups for this study included 84 elderly participants with NC and 43 elderly participants with MCI who received comprehensive cognitive health management. The control groups included 84 elderly participants with NC and 43 elderly participants with MCI who matched the intervention group’s general characteristics and scale scores using the propensity matching score analysis. The Montreal Cognitive Assessment (MoCA) scale and Geriatric Depression Scale (GDS) scores were compared after a 1-year follow-up.Results For older adults with MCI in the intervention group, MoCA scores were higher at the 1-year follow-up than at baseline (24.07 (3.674) vs 22.21 (3.052), p=0.002). For the MoCA subscales, the intervention group’s abstract and delayed memory scores had significantly increased during the 1-year follow-up. Furthermore, in a generalised linear mixed model analysis, the interaction effect of group×follow-up was statistically significant for the MCI group (F=6.61, p=0.011; coefficients=5.83).Conclusions After the comprehensive cognitive health management intervention, the older adults with MCI in the community showed improvement at the 1-year follow-up. This preliminary study was the first to demonstrate an easy-to-implement strategy for modifying the cognitive risk factors of elderly individuals with MCI in the community, providing new insight into early-stage intervention for dementia.No data are available. No additional data are available.