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Concomitant atopic dermatitis and narcolepsy type 1: psychiatric implications and challenges in management
  1. Justin Chin1,
  2. Craig Bearison2,
  3. Nanette Silverberg3 and
  4. Mary Lee Wong4,5
  1. 1 Department of Primary Care, Touro College of Osteopathic Medicine, New York City, New York, USA
  2. 2 Department of Internal Medicine, Beth Israel Medical Center, New York City, New York, USA
  3. 3 Department of Pediatric Dermatology, Mount Sinai Health System, New York City, New York, USA
  4. 4 Department of Allergy and Immunology, Beth Israel Medical Center, New York City, New York, USA
  5. 5 Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, New York, USA
  1. Correspondence to Mr Justin Chin; jchin2{at}student.touro.edu

Abstract

Atopic dermatitis (AD) and narcolepsy type 1 (NT1) are two distinct diseases that have not been classically shown to be related. The potential connection between the known immunological aetiology of AD and the proposed autoimmune pathophysiology of dysregulation in NT1; however, is the subject of ongoing speculation and debate with advances in gene sequencing and technology. Here, we present a case of a patient with concomitant refractory AD and NT1 and review the current research on their immunological relationship and the challenges in management relative to disease burden and psychiatric comorbidities.

  • atopic dermatitis
  • narcolepsy
  • anxiety
  • eczema
  • immunology

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Footnotes

  • Contributors JC contributed to the literature review. CB and MLW contributed to the data collection. JC, CB and NS developed the manuscript. All authors contributed to the concept development and edited the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.