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We consider that the intestinal microbiota is not only related to anxiety disorders. The microbiota-gut-brain axis is related to multiple mental disorders. If we start from the phrase "we are what we eat" we should pay better attention to a healthy diet and support Hippocrates when he said "let food be your best medicine and your best medicine be your food". We know the microbiota as the set of microorganisms that live symbiotically in a given ecological niche, in this case it refers to the intestinal microbiota where there are native species that colonize the gastrointestinal tract and a variable series of living microorganisms that are transiting through the tube digestive. Anaerobic germs predominate, bacteroides, bifidobacterium, eubacterium, clostridium, lactobacillus. The evolution of the microbiota varies from the fetal stage to adulthood and factors that modify it intervene in this evolution: diet, pH, oxygen concentration, nutrient availability, stress, genetic factors, the use of antibiotics, lactation maternal, prematurity, caesarean section among others. There is a bidirectional and dynamic communication between the intestine and the brain through nervous, endocrine and immune signaling pathways, so the role of neurotransmitters, hormones, metabolites, cytokines is fundamental in the appearance of mental illnesses that are reference.