You are here

  • Home
  • Archive
  • Volume 31, Issue 3
  • CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis

Article Text

Article menu

Download PDFPDF

Case report
CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
  1. Dheerendra Kumar Mishra1,
  2. Aman Kishore2 and
  3. Vijay Niranjan3
  1. 1 Department of Psychiatry, Shyam Shah Medical College Rewa, Rewa, Madhya Pradesh, India
  2. 2 Masik Aarogyashala Gwalior, Indore, Madhya Pradesh, India
  3. 3 Department of Psychiatry, M. G. M. Medical College Indore, Indore, Madhya Pradesh, India
  1. Correspondence to Dr Dheerendra Kumar Mishra; mdheerendra.ssmc{at}gmail.com

Abstract

Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is the most common monogenic form of cerebral small-vessel disease characterised by recurrent strokes. Behavioural disturbance also presents in a significant proportion of subjects as neurotic spectrum disorders and psychotic features are rarely reported. In this case report, we highlight a 32-year-old man with CADASIL syndrome, who had overt psychotic symptoms with neurological signs later on.

  • CADASIL
  • psychosis
  • syndrome
  • genetic strokes

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0

https://doi.org/10.1136/gpsych-2018-100017

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors DKM: collected data and summarised the case. AK: conceptualised and supervised the project. DKM, VN: contributed to drafting, revising and final version of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Parental/guardian consent obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.