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Assessing the Accuracy of Diagnostic Tests
  1. Fangyu Li and
  2. Hua He
  1. Department of Epidemiology, Tulane University School of Public Health and Tropic Medicine New Orleans, USA
  1. correspondence: Hua He. Mailing address: 1440 Canal Street, Suite 2000, New Orleans, LA, USA; Postcode: LA 70122; E-Mail: hhe2{at}


Gold standard tests are usually used for diagnosis of a disease, but the gold standard tests may not be always available or cannot be administrated due to many reasons such as cost, availability, ethical issues etc. In such cases, some instruments or screening tools can be used to diagnose the disease. However, before the screening tools can be applied, it is crucial to evaluate the accuracy of these screening tools compared to the gold standard tests. In this assay, we will discuss how to assess the accuracy of a diagnostic test through an example using R program.

  • AUC
  • gold standard test
  • ROC analysis
  • ROC curve
  • sensitivity
  • specificity

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